Treatments / Rx (info only)
Guanfacine with NAC
Over $50
Grade None
Info only
Evidence estimate
Not enough reports from people 1+ years in yet
40% overall
Overview
Prescription information only. Discussed in some long COVID clinics together with NAC.
Mechanisms it may act on
- Immune / post-viral Plausible
- Energy-limited Plausible
Where the estimate comes from
- From studies (prior): 2.0
- From Reddit reports: 1.4
- From investigators here: 0.0
- From tests: 0.0
Studies
-
TREATME survey of treatments for long COVID and ME/CFS2025 · PNAS · n=3925 · Positive · PubMed TREATME-PNAS-2025
-
Atomoxetine on neurogenic orthostatic hypotension: a randomized, double-blind, placebo-controlled crossover trial.2024 · Clinical autonomic research : official journal of the Clinical Autonomic Research Society · n=68 · Null · PubMed 39294522
Reddit reports
Coded from public Reddit posts. People who post tend to have strong results either way.
- Helped: 3
- Partly: 2
- No change: 2
- Worse: 0
How people usually try it
Talk to your doctor. This card is for search and context, not a protocol you run here.
Typical dose: Clinician-directed
Safety
Prescription. Talk to your doctor.
Prescription. Talk to your doctor.
Not medical advice, not a diagnosis, and not a substitute for a clinician.