No alcohol trial

Overview

Remove alcohol completely for two weeks and watch what happens to your fog.

Mechanisms it may act on

• Sleep & rhythm Strong
• Histamine-reactive Plausible

Where the estimate comes from

• From studies (prior): 2.0
• From Reddit reports: 0.2
• From investigators here: 0.0
• From tests: 0.0

Studies

• Oral Choline Reduced Working Memory-Related Brain Activation in Postmenopausal Women: A Pilot Study.
  2026 · Nutrients · n=20 · Mixed · PubMed 41683281
• Impacts of aerobic exercise and whole-body vibration interventions on myokines and neurocognitive performance in postmenopausal women.
  2025 · Physiology & behavior · n=23 · Positive · PubMed 40912347
• Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndrome.
  2023 · Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · n=39 · Positive · PubMed 36455453
• Low Dose Naltrexone in the Treatment of Fibromyalgia.
  2018 · Current rheumatology reviews · n=? · · PubMed 28325149
• Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia.
  2018 · The Cochrane database of systematic reviews · n=7903 · Positive · PubMed 29489029
• Heart rate variability decreases after 3 months of sustained treatment with fingolimod.
  2017 · Journal of neurology · n=33 · · PubMed 28993873
• Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome.
  2013 · The Cochrane database of systematic reviews · n=6038 · Positive · PubMed 23440848
• A healthy dietary pattern at midlife is associated with subsequent cognitive performance.
  2012 · The Journal of nutrition · n=? · Positive · PubMed 22457391
• Administration of dehydroepiandrosterone (DHEA) enhances visual-spatial performance in postmenopausal women.
  2011 · Behavioral neuroscience · n=24 · Positive · PubMed 21942436
• Mild cognitive impairment and dementia: the importance of modifiable risk factors.
  2011 · Deutsches Arzteblatt international · n=? · · PubMed 22163250

Reddit reports

Coded from public Reddit posts. People who post tend to have strong results either way.

• Helped: 1
• Partly: 0
• No change: 0
• Worse: 0

How people usually try it

No alcohol at all for the on phase. Keep everything else the same so the result means something.

Typical dose: Zero drinks