Magnesium glycinate

Overview

An evening magnesium form some investigators use for sleep-related fog.

Mechanisms it may act on

• Sleep & rhythm Plausible

Where the estimate comes from

• From studies (prior): 2.0
• From Reddit reports: 2.6
• From investigators here: 0.0
• From tests: 0.0

Studies

• Quantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
  2026 · Aging clinical and experimental research · n=22 · Null · PubMed 41566091
• Effects of Coenzyme Q10, Tryptophan, and Magnesium Supplementation on Fatigue in Patients with Fibromyalgia - A Randomized Trial.
  2025 · Journal of dietary supplements · n=35 · Negative · PubMed 40151031
• Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial.
  2022 · Nutrients · n=? · Mixed · PubMed 35631229
• Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain.
  2020 · Nutrients · n=52 · Positive · PubMed 32751522
• Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
  2017 · Scientific reports · n=52 · Null · PubMed 28273891
• [Long-term HRV analysis shows stress reduction by magnesium intake].
  2016 · MMW Fortschritte der Medizin · n=100 · Positive · PubMed 27933574
• Metabolic Correction as a tool to improve diabetes type 2 management.
  2015 · Boletin de la Asociacion Medica de Puerto Rico · n=25 · Positive · PubMed 26434085

Reddit reports

Coded from public Reddit posts. People who post tend to have strong results either way.

• Helped: 8
• Partly: 3
• No change: 2
• Worse: 0

How people usually try it

Take in the evening with water. Reduce dose if stools loosen.

Typical dose: 200-400 mg elemental at night